There's a new genetic DNA test for "Grey Collie Syndrome" or as it's officially known......Canine Cyclic Neutropenia.
A blood disorder that is present at birth, affected puppies are smaller and weaker, with a noticeable pale gray or pinkish/gray or beige color. This blood disorder affects red and white blood cell production approximately every 10 to 12 days. Due to the cyclic nature of the disease, these puppies rarely live beyond a couple of days and when they do survive, they are extremely susceptible to all sorts of infections. With treatment they can be kept alive, but few have lived beyond a couple of years old.
Gray Collies have been documented in many different Collie bloodlines for more than 60 years and coincidentally the disease is also present in humans. Both sire and dam need to be carriers in order for the gene to present itself (autosomal recessive). However, it should be noted that carriers do not manifest the disease.
Please see the HealthGene Corp. website
for more information on testing your Collie - http://healthgene.com/canine/C136.asp