The Collie Health Foundation is delighted to announce the creation of a YouTube channel! First up – Dr. Leigh Anne Clark Presentation on Dermatomyositis & Interpreting Risk Assessment Results, from March 29, 2018 at the Collie National in Virginia Beach. Special thanks to Irv and June Krukenkamp, Show Dog Video Pros, for capturing this presentation in such quality and making it possible to share with all!
Optimal Selection (TM) Canine Genetic Breeding Analysis
The Optimal Selection (TM) panel tests for over 180 different genetic health markers, 20 different traits, and genetic diversity. Most of these tests have nothing to do with our Collie Breed. The exciting news is that this tests covers 7 health test and traits that are very important for Collies and the people that breed them. Here are the pertinent tests:
- MDR1 – MultiDrug Resistance (Licensed by Washington State University – VetMed)
- CCN – Canine Cyclic Neutropenia – Grey Collie
- DM – Degenerative Myelopathy
- CEA – Collie Eye Anomaly – (MARS purchased OptiGen in 2018 and owns the rights to the testing method)
- Coat Trait – Length ( Rough factored Smooth)
- Color Traits – Color and Patterns including Merle
- GENETIC DIVERSITY – “The Breeders Tool Box”
- Diversity of the individual dog tested
- Diversity of the overall breed population
- Diversity of the overall breed population compared to the diversity of other related breed populations
Testing organization: MARS, Wisdom Health
Regular Price: $130 – Add CEA at 20 Euros or approximately $25 – total $155
Rebate: $90 without CEA – $110 with CEA
Method and Test Ordering Instructions: Oral cheek swab.
Optimal Selection Canin Genetic Breed Analysis
NOTE: REBATES ARE FOR ROUGH AND SMOOTH COLLIES ONLY & for CHF Members
Dermatomyositis (DMS) Risk Assessment
Dermatomyositis (DMS) is a hereditary condition of the skin and muscle, resulting from an unknown inflammatory process. This can present most commonly with hair loss, redness, scaling, crust formation, and vesicles (a type of red bump or bubble on the skin). Some dogs may also suffer from myosotis, an inflammation of muscle. This can result in a loss of muscle, and in severe cases may affect drinking, swallowing and eating.
The CHF Board has recently voted to offer a rebate of $65, or your cost of testing if less, to all CHF members. This test is done by cheek swab. This offer is through 12/31/19 with no limits on the number of rebates per household. You will need to provide your test results email or paper. Please feel free to blackout the results. NOTE: REBATES ARE FOR ROUGH AND SMOOTH COLLIES ONLY
OptiGen will be partnering with the CHF and offering a 25% discount on CEA tests throughout 2018. Price for one test is $100. If PRA testing is done together, price is $90 per test. After CHF member rebate and OptiGen discount, it brings the cost down to $10 for one test, or $2.50 or less each for two or more tests. The code CHF19REF should be used through the end of 2019.
Please see the OptiGen website for information on testing: http://www.optigen.com/opt9_test_cea_ch.html
Canine Cyclic Neutropenia (Gray Collie Syndrome):
The CHF Board has voted to offer a rebate of $90 or $110 including CEA for the Optimal Selection(tm) Panel test, which includes Gray Collie, to all CHF members. This offer is through 12/31/19 with no limits on the number of rebates per household. For more information go to Research and Testing. NOTE: REBATES ARE FOR ROUGH AND SMOOTH COLLIES ONLY
Cyclic Neutropenia (CN) is a recessive stem cell disorder that affects both smooth and rough collies. Also known as Cyclic Hematopoiesis or “Gray Collie Syndrome,” dogs affected by Cyclic Neutropenia appear visibly lighter than non-affected littermates – even from puppies with the Merle coloration.
Cyclic Neutropenia is a disease that affects the neutrophils of a dog, which are an integral part of the dog’s immune system. Every 10-12 days, the dog will experience a dramatic drop in the number of neutrophils circulating through his blood stream, leaving him extremely susceptible to infections. The dog will often experience diarrhea, fever, joint pain or other symptoms associated with eye, respiratory, or skin infections. Bleeding episodes can also occur. Unfortunately, most affected dogs will die as puppies, and even with the best care, the dog will not likely live past 2-3 years of age.
Gray Collie Syndrome is an autosomal recessive mutation, meaning that a dog must have two copies of the mutation in order to display the signs and symptoms associated with this disorder. This also means that a parent can be a carrier of this disorder but not show any signs. A dog that carries the mutation can pass on either the normal or mutant allele to any offspring. Therefore, if two carriers produce a litter of pups, there is a 1 in 4, or 25% chance that an offspring will be affected by the disorder. Additionally, 50% of the pups will be carriers and 25% will be clear.
Progressive Retinal Atrophy (PRA-rcd2)
The PRA test (rod-cone dysplasia Type 2 ) is available through OptiGen. The normal price for this test is $130 per dog. As an incentive to test, the Collie Health Foundation will offer – to Collie Health Foundation members – a $50 refund per test with no limits. This special pricing will remain in effect until 12/31/18.
OptiGen will be partnering with the CHF and offering a 25% discount on PRA-rcd2 tests throughout 2018. Price for one test is $104. If DMS and PRA testing is done together, price is $96 per test. After CHF member rebate, it brings the cost down to $54 for one test or $46 each for two tests. The code CHF19REF should be used through the end of 2019. You will need to provide your test results, blacked out if you wish, for the rebate. NOTE: REBATES ARE FOR ROUGH AND SMOOTH COLLIES ONLY
Please see the OptiGen website for information on testing: http://www.optigen.com/opt9_rcd2testpage.html
DNA for this test can be gathered using a cheek swab, blood, or semen. The rcd2 mutation causes abnormal development (Dysplasia) of the cones and rods (the light sensitive cells in the eye) which leads to an early onset of night blindness that is readily apparent by the time the pup is 6 weeks of age. In most cases, the rcd2-affected dog is completely blind by one year of age.
More information on this disorder can be found by going to Health Issues, Articles on our website for more information on this disease.
Collie Eye Anomaly (CEA)
Collie Eye Anomaly is a recessively inherited eye disorder that causes abnormal development of the choroid – an important layer of tissue under the retina of the eye. The CEA test is available through the Optimal Selection(tm) Panel test as an add on test after you have received your results. The normal price for this test including CEA is approximately $155 per dog. The Collie Health Foundation will offer – to Collie Health Foundation members – a $110 refund per test when CEA has been added on. This special pricing, with no limits, will remain in effect until 12/31/19.
DNA for this test can be gathered using a cheek swab.
Multi-Drug Resistant gene (MDR1)
MDR1 is a multidrug sensitivity including antiparasitics, anticancer agents, environmental pesticides and others, which can cause severe reactions, even death, in some Collies. The discovery of the mutation of the multi-drug resistant gene (MDR1), establishment of testing procedures, and development of all reagents was made by Washington State University. WSU recently licensed Wisdom Health and their Optimal Selection(tm) test for MDR1 testing. CHF knows suggest all breeders use the Optimal Selection Test, because of all of the tests include genetic diversity that are offered. Collie owners who will not be breeding, members with rescue dogs will still be able to test through WSU and receive the $20 rebate
New Pricing on MDR1 testing:
$60 per test when paid online. CHF offers a rebate of $20 per test to CHF Members when testing through Washington State University. This brings the price down to $40 after rebate. Remember, only WSU, VCPL (Veterinary Clinical Pharmacology LAB), has the patent on testing for the MDR1 gene. The rebate remains in effect until 12/31/18. Please go to Research and Testing for links to testing. NOTE: REBATES ARE FOR ROUGH AND SMOOTH COLLIES ONLY
For more information, go to the Washington State website: http://vcpl.vetmed.wsu.edu/problem-drugs
DNA for this test is gathered using a cheek swab. More information on this disorder can be found by going to Health Issues, Articles on our website for more information on this disease.
How to submit for your CHF subsidy refund:
You can submit your paid receipt to the CHF Assistant Treasurer for your rebate.
Send to: Collie Health Foundation, Inc., Krista Hansen, 1525 Minkel Road, North Java, NY 14113