Associated Immunosuppression in a Dog Heterozygous for the MDR1 (ABCB1-1Δ) Mutation Abstract Pharmacodynamic monitoring was used to titrate cyclosporine dosing in a dog with immune-mediated hemolytic anemia. Development of a suspected secondary infection, with subsequent discovery of an unexpectedly high level of T-cell suppression despite a relatively low cyclosporine dose, prompted an investigation into the [...]
By Robette Johns Donna’s story highlights the fact that no matter how careful we are or how many times we tell our vet clinic our Collie is MDR1 mutant/mutant, it’s never enough. To give you a little background on the MDR1 journey, one of Pati Merrill’s memorable stories about “Getting to Know You”, in the [...]
The Collie Health Foundation has had an extraordinarily long and strong working relationship with OptiGen Labs. After OptiGen was purchased by Wisdom Health, a division of MARS, I was extremely worried. I was able to talk with Sue Pearce Kelling not to long after the announcement was made, Sue set up a time where I [...]
Part I – Where to Test (AKA the Lab) Not all labs are alike. Until we have universal standards, you as the breeder need to rely on someone you trust to tell you what testing agency might be right for your breed of dog. Consider the following: You are getting ready to breed Lassie and [...]
You Think Figuring Out Health Testing is Too Hard? I have heard a lot of complaints lately about how difficult it is to figure out heath testing and applying for subsidies. I was really taken aback by this. Since the Collie Health foundation has multiple purposes, and one is education, this hit me hard. When I [...]
Still a Breeder’s Nightmare? Many things have changed since I wrote my first article almost twenty years ago, but many other things have not. Over the years, I have continued to learn things about DMS in Collies and in people. I hope this helps you as a Collie breeder, owner and fancier to be more [...]
YouTube Video - Rediscovered video of the first CHF Gathering at Sunnybank Click the CC on the bottom right for Closed Captioning once you start the video.
YouTube Video - Collie Health Foundation Seminar on Hip & Elbow Dysplasia, OFA and Pennhip Click the CC on the bottom right for Closed Captioning once you start the video.
Vesicular Cutaneous Lupus Erythematosus in Dogs Introduction Vesicular cutaneous lupus erythematosus (VCLE) is a variant form of cutaneous lupus erythematosus (CLE) that affects predominantly adult rough collies, Shetland sheepdogs and Border collies. Distinctive cutaneous lesions consist of annular, polycyclic and/or serpiginous erosions and ulcerations, primarily affecting the axillae, ventral abdomen and groin with frequent involvement [...]
YouTube Video on Dermatomyositis & Interpreting Risk Assessment Results Click the CC on the bottom right for Closed Captioning once you start the video.