Dermatomyositis DMS

Study Information

Description of Study Topic: Dr. Leigh Anne Clark’s genetics lab at Clemson University is looking for additional gene(s) underlying development of DMS in collies.

Method and Test Study Information: Cheek swabs samples are requested from collies that have been diagnosed by skin punch biopsy. Dogs that have not been diagnosed by skin punch biopsy but are strongly suspected of having DMS may also be eligible. Participants will be provided with DMS risk assessment results.

Leigh Anne Clark, PhD
(864) 656-4696
154 Poole Agricultural Center
130 McGinty Ct.
Dept. of Genetics & Biochemistry
Clemson University
Clemson, SC 29634-0318

PRA & Coloboma

Study Information: PRA and Coloboma Research 

Description of Study Topic: Dr. Gustavo Aguirre, VMD, PhD, University of Pennsylvania and OptiGen, LLC is supporting further research in both of these areas.

Method and Test Study Information: OptiGen is offering free DNA testing for pedigreed dogs that have been diagnosed by a board certified veterinary ophthalmologist. OptiGen is collecting samples from (non-merle) pedigreed dogs that have been diagnosed with optic nerve colobomas.
To read more please visit the OptiGen Research webpage.

Contact: or contact OptiGen at

Von Willebrand’s Disease – vWD

Study Information:

Identification of Von Willebrand’s Disease (vWD) causal mutation and development of a direct DNA test

Description of Study Topic: CHF is currently funding a grant looking for participants – collies that bleed excessively or unexpectedly.

Method and Test Study Information: Swabs available by contacting Ann Arnold at VetGen for details.  Please include a blood assay test if your veterinarian has done one.

3728 Plaza Drive, Suite 1
Ann Arbor, Michigan, 48108 USA
Phone: (734) 669-8440
(800) 483-8436, (800) 483-8436 (US & Canada)
Fax: (734) 669-8441
VetGen Email: VetGen vWD2


Study Information:

Evaluating the Complex Genetic Basis of Bloat

Description of Study Topic: Dr. Claire Sharp and her team at Tufts University are looking to collect blood (in EDTA anticoagulant) for the extraction of DNA from dogs that have had GDV or are from at risk breeds that have not had GDV. The DNA samples will be used for a genome wide association study in at risk breeds in order to identify single nucleotide polymorphisms that are associated with increased risk for GDV. This is part of a larger study evaluating the pathophysiology of GDV from a systems biology perspective.

Method and Test Study Information: Blood sample; contact Dr. Sharp for details.

Dr. Claire Sharp BVMS
Tufts University

Study Information:

Abnormalites in the Stomach’s Ability to Contract Predisposes Large-Breed Dogs to Bloat

Description of Study Topic: The goals of Dr. Nelson’s study are to determine the relationship of abnormal stomach contraction with GDV and to define the biochemical and genetic alterations that may be associated with these stomach abnormalities. In the long term, they hope to develop a test to identify dogs at high risk for GDV that would allow selective breeding to eliminate the condition and to determine which dogs will benefit most from prophylactic gastropexy or other preventive therapies

Method and Test Study Information: Contact Dr. Nelson for information

Dr. Laura L. Nelson, DVM, MS, Diplomate ACVS
Michigan State University Small Animal Clinical